At least four people have been killed and more than 300 injured during clashes between rival political groups in Cairo, according to Egypt’s Health Ministry.

The violence centered around the presidential palace, but there have also been attacks on the headquarters of the Freedom and Justice Party, formerly led by President Mohamed Mursi.

Muslim Brotherhood offices in the cities of Ismailia and Suez have also been torched.

Opposition groups in Egypt have been demanding the president rescind decrees made in 22 November, allowing him to take any measures that would protect the revolution and the national security of Egypt. The decrees also state that no judicial authority can dissolve the constituent assembly or the upper house of parliament and that no court could dispute his decisions.

Secular and liberal groups have also demanded Mursi scrap the draft constitution drawn up by Egypt’s constituent assembly, now dominated by Muslim Brotherhood allies. Egypt is set to elect a new parliament following a referendum on the constitution planned for 15 December.

Mursi has so far refused to back down on his decrees, insisting they are temporary and will not have effect once a constitution is passed. So far, six members of his advisory staff have resigned following the decree.