Qatar Investment Authority (QIA) has put the Canary Warf tower 1 Cabot Square up for sale for £450m ($653m) amid persistently low global oil prices.
The building is home to investment bank Credit Suisse and it is the sovereign wealth funds first major London property to be put up for sale.
It was bought by QIA in 2012 for £330m.
The authority took control of the Canary Wharf Group in 2015. Canary Wharf Group is owner and developer of nearly 100 acres of property in the Canary Wharf area.