The new building will be for the faculty of medicine and the estimated value of the contract is SR500m ($136m).
Bids are expected to be submitted in two months. The Higher Education Ministry is the client.
It is the latest in a series of university projects in the kingdom.
Saudi Oger is currently building the SR11.3bn King Abdullah University of Science & Technology for Saudi Aramco near Jeddah in the west of the kingdom.
Bids were also submitted recently for the SR8bn King Saud University for Girls in Riyadh (MEED 25:7:08).
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